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The peptide influences vasomotor tone through the Src-caveolin-1-eNOS pathway, affecting both vasoconstriction and vasodilation depending on baseline vascular state

FIGURE 3 PEROXIREDOXINTHIOREDOXIN REDOX CYCLE Peroxiredoxins constitute a family of thiol-specific peroxidases that rely on thioredoxins (Trxs) as the hydrogen donor for the reduction of H 2 O 2 and lipid hydroperoxides ( 2 O 2 produced by the mitochondrial respiratory chain

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The molecule exists in two forms: reduced glutathione (GSH), which is the active form, and oxidized glutathione (GSSG)